Jeffrey Epstein had information on Donald Trump and the Clintons so incendiary, it could have upended the 2016 presidential election if made public, according to the dead financier’s younger brother.

“Here’s a direct quote: ‘If I said what I know about both candidates, they’d have to cancel the election.’ That’s what Jeffrey told me in 2016,” Mark Epstein told The Post Wednesday, recalling a conversation he had with his brother about the showdown between Trump and Hillary Clinton.

However, property developer Mark, 69, demurred when pushed to elaborate, saying his brother never revealed to him exactly what he knew about the then-presidential hopefuls.

Both candidates were known to have moved within Epstein’s circle, either directly or indirectly.

Trump flew on Epstein’s private jet seven times in the ’90s, according to flight logs, jetting between Palm Beach, Florida, and New York, accompanied by family members on at least two occasions.

Hillary is not known to have consorted with Epstein personally, but her husband, former President Bill Clinton, was a friend of Epstein dating back to at least 1993 during his first term in the White House.

Bill and Epstein visited each other numerous times over the years — including Epstein making at least 17 visits to the White House.

The ex-president also traveled across the world aboard Epstein’s jet, making trips to Europe, Asia and Africa in 2002 and 2003.

Mark said his brother taking Clinton on a philanthropic trip to Africa was what first put him under scrutiny.

He added: “Well, when Jeff first took Clinton and I think it was Chris Tucker and some other people to Africa — which was a mistake my brother made by doing that, because prior to that he was under the radar; nobody was looking at him.

“But when he flew Clinton there, it was like, ‘Who’s this guy flying Clinton?’” 

Epstein’s jet was later notoriously dubbed “the Lolita Express” as he used it to sex-traffic underage girls between his various properties.

Clinton is expected to be identified as “John Doe 36” in a trove of court documents related to Epstein set to be released Wednesday.

The 77-year-old is mentioned at least 50 times across the documents, which come from a 2015 lawsuit by Epstein accuser Virginia Giuffre against his right-hand woman, Ghislaine Maxwell.

Maxwell, a co-conspirator in the sex ring who is now jailed in Florida, allegedly claimed Epstein had video tapes showing Trump and Clinton in compromising positions with women.

“If you get the tapes on Trump, you have to do Clinton,” Maxwell said during a 2016 interview, former “60 Minutes” producer Ira Rosen alleged in his book, “Ticking Clock: Behind the Scenes at 60 Minutes.”

Maxwell then allegedly said she didn’t know where the tapes were located.

No such tapes have ever come to light.

However, Clinton is not expected to be implicated in any illegal activity, ABC News reported, and has never been accused of any wrongdoing in relation to anyone in Epstein’s orbit.

Giuffre has alleged she met Clinton on Epstein’s private Caribbean Island, Little St. James, where the sex offender committed many of his lewd and horrific crimes. Clinton has denied ever visiting the island, and currently available flight records support his claims.

In July 2019, after Epstein had been arrested in New York and charged for a second time with sex crimes involving underage girls, a spokesperson for Clinton said he knew “nothing about the terrible crimes Jeffrey Epstein pleaded guilty to in Florida some years ago, or those with which he has been recently charged in New York.”

A little over a month later, Epstein hanged himself in his prison cell.

It is unclear whether Trump will appear in the documents, but his known interactions with Epstein, including pictures of them socializing, suggest he could.

At least 170 people with ties to Epstein — previously known only as John and Jane Does — are expected to be publicly identified following a ruling by Manhattan federal Judge Loretta Preska to release the files.

Many of the names are expected to be previously known associates, co-conspirators or employees of Epstein, and many previously anonymous accusers are expected to be named.

Mark Epstein, who believes his brother was murdered after his 2019 arrest and did not commit suicide, does not expect much to come of the files.

“My brother used to have conferences on the island with noted mathematicians and scientists. So now they’re going to get smeared because they participated in one of these scientific panels?” he told The Post.

“It’s not my job to defend my brother. That’s not what I’m here for. The only thing I’m looking at is the circumstances of his murder,” he added.

The Post’s requests for comment to both Trump and Clinton were not immediately returned.