ALPHARETTA, Ga.—Unless something unexpected happens in the next few months, the 2024 presidential campaign is likely to feature two aging, retread candidates of whom Americans are thoroughly tired. On Thursday, however, a different reality was on display: two energetic partisans in their prime, holding each other to account on issues of substance and presenting a clear choice to voters.

Florida Gov. Ron DeSantis, a Republican, and California Gov. Gavin Newsom, a Democrat, faced off in a no-holds-barred roughly 100-minute debate, moderated by Fox News’s Sean Hannity and airing live on the cable network. Wall Street Journal parent News Corp and Fox parent Fox Corp. share common ownership.

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